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Invitrogen
MAGE1 Monoclonal Antibody (6C1)
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FIGURE: 1 / 10
MAGE1 Antibody (35-6300) in IHC
Veterinary sciences 2020 -
Figure 3 Positive cross-reactivity of MAb 6C1, mammary gland tumors and canines. Location of MAGE expression in the complex carcinoma type of malignant mammary gland tumor section Ma1: ( a ) HE stained, 40x; ( b ) IHC-stained-positive, 40x; ( c ) IHC-stained-positive, 100x black arrows are representative of nuclear expression pattern; red arrows are representative of nuclear-cytoplasmic expression pattern.
Product Details
35-6300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Dog,
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
6C1
Immunogen
Full-length recombinant human MAGE-A.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533216
Target Information
Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antigen MZ2-E; Cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CT1.1; mage 1; mage-1; MAGE-1 antigen; melanoma antigen family A 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; Melanoma-associated antigen 1; melanoma-associated antigen MZ2-E
Gene Aliases: CT1.1; MAGE1; MAGE1A; MAGEA1
UniProt ID: (Human) P43355
Entrez Gene ID: (Human) 4100
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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