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Product Details
14602-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAGEA6 Fusion Protein Ag6148 (1-314 aa encoded by BC067731)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPLEQRSQH CKPEEGLEAR GEALGLVGAQ APATEEQEAA SSSSTLVEVT LGEVPAAESP DPPQSPQGAS SLPTTMNYPL WSQSYEDSSN QEEEGPSTFP DLESEFQAAL SRKVAKLVHF LLLKYRAREP VTKAEMLGSV VGNWQYFFPV IFIKASDSLQ LVFGIELMEV DPIGHVYIFA TCLGLSYDGL LGDNQIMPKT GFLIIILAII AKEGDCAPEE KIWEELSVLE VFEGREDSIF GDPKKLLTQY FVQENYLEYR QVPGSDPACY EFLWGPRALI ETSYVKVLHH MVKISGGPRI SYPLLHEWAL REGEE (1-314 aa encoded by BC067731)
Target Information
MAGEA6 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cancer/testis antigen 1.6; cancer/testis antigen family 1, member 6; CT1.6; MAGE-6 antigen; MAGE3B antigen; melanoma antigen family A, 6; melanoma antigen family A6; Melanoma-associated antigen 6
Gene Aliases: CT1.6; MAGE-3b; Mage-a6; MAGE3B; MAGE6; MAGEA6
UniProt ID: (Human) P43360
Entrez Gene ID: (Human) 4105, (Mouse) 17142
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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