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Immunogen sequence: EGLSVVFGLE LNKVNPNGHT YTFIDKVDLT DEESLLSSWD FP
MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 3.2; cancer/testis antigen family 3, member 2; CT3.2; DAM6; DSS-AHC critical interval MAGE superfamily 6; DSS/AHC critical interval MAGE superfamily 6; MAGE XP-2 antigen; MAGE-B2 antigen; melanoma antigen family B, 2; melanoma antigen family B2; Melanoma-associated antigen B2; MGC26438
Gene Aliases: CT3.2; DAM6; MAGE-XP-2; MAGEB2
UniProt ID: (Human) O15479
Entrez Gene ID: (Human) 4113
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