Proteintech

MAGOH Polyclonal Antibody

MAGOH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 9

MAGOH Antibody (12347-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using 12347-1-AP ( MAGOH antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

MAGOH Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12347-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MAGOH Fusion Protein Ag3004 (1-146 aa encoded by BC018211)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MESDFYLRY YVGHKGKFGH EFLEFEFRPD GKLRYANNSN YKNDVMIRKE AYVHKSVMEE LKRIIDDSEI TKEDDALWPP PDRVGRQELE IVIGDEHISF TTSKIGSLID VNQSKDPEGL RVFYYLVQDL KCLVFSLIGL HFKIKPI (1-146 aa encoded by BC018211)

Target Information

Drosophila that have mutations in their mago nashi gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity.

Nucleic acids research

Li D,Yang J,Malik V,Huang Y,Huang X,Zhou H,Wang J

Mon Nov 28 00:00:00 UTC 2022

NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis.

Cell metabolism

Park MK,Zhang L,Min KW,Cho JH,Yeh CC,Moon H,Hormaechea-Agulla D,Mun H,Ko S,Lee JW,Jathar S,Smith AS,Yao Y,Giang NT,Vu HH,Yan VC,Bridges MC,Kourtidis A,Muller F,Chang JH,Song SJ,Nakagawa S,Hirose T,Yoon JH,Song MS

Tue Dec 07 00:00:00 UTC 2021

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.

Cell reports

Kuzuoglu-Ozturk D,Hu Z,Rama M,Devericks E,Weiss J,Chiang GG,Worland ST,Brenner SE,Goodarzi H,Gilbert LA,Ruggero D

Tue Jun 29 00:00:00 UTC 2021

Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.

Development (Cambridge, England)

Sheehan CJ,McMahon JJ,Serdar LD,Silver DL

Mon Jan 13 00:00:00 UTC 2020

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.

PLoS genetics

Mao H,McMahon JJ,Tsai YH,Wang Z,Silver DL

Thu Sep 01 00:00:00 UTC 2016

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.

PLoS genetics

Mao H,McMahon JJ,Tsai YH,Wang Z,Silver DL

Thu Sep 01 00:00:00 UTC 2016

Generation of a Magoh conditional allele in mice.

Genesis (New York, N.Y. : 2000)

McMahon JJ,Shi L,Silver DL

Fri Aug 01 00:00:00 UTC 2014

Generation of a Magoh conditional allele in mice.

Genesis (New York, N.Y. : 2000)

McMahon JJ,Shi L,Silver DL

Fri Aug 01 00:00:00 UTC 2014

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Nature neuroscience

Silver DL,Watkins-Chow DE,Schreck KC,Pierfelice TJ,Larson DM,Burnetti AJ,Liaw HJ,Myung K,Walsh CA,Gaiano N,Pavan WJ

Sat May 01 00:00:00 UTC 2010

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Nature neuroscience

Silver DL,Watkins-Chow DE,Schreck KC,Pierfelice TJ,Larson DM,Burnetti AJ,Liaw HJ,Myung K,Walsh CA,Gaiano N,Pavan WJ

Sat May 01 00:00:00 UTC 2010

Mago, a vertebrate homolog of Drosophila Mago nashi protein, is a component of the chromatoid body in the cytoplasm of the postmeiotic spermatid.

Journal of experimental zoology. Part B, Molecular and developmental evolution