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Proteintech
MAML1 Polyclonal Antibody
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Product Details
55493-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to MAML1. The calculated molecular weight of MAML1 is 108 kDa, but modified MAML1 is about 120 kDa.
Target Information
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ53540; Mam-1; MAML1; mastermind homolog; mastermind-like 1; Mastermind-like protein 1; mastermind-like transcriptional coactivator 1
Gene Aliases: AI644666; AW743257; D930008C07Rik; KIAA0200; Mam-1; Mam1; MAML1; mKIAA0200
UniProt ID: (Human) Q92585, (Mouse) Q6T264
Entrez Gene ID: (Human) 9794, (Rat) 303101, (Mouse) 103806
protein phosphorylation
Notch signaling pathway
positive regulation of transcription of Notch receptor target
positive regulation of myotube differentiation
myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of muscle cell differentiation
atrioventricular node cell development
atrioventricular node development
transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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