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Invitrogen
MAN2A1 Polyclonal Antibody
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Product Details
PA5-76526
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human MAN2A1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2720253
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-mannosidase 2; alpha-mannosidase II; AMan II; Golgi alpha-mannosidase II; golgi integral membrane protein 7; MAN II; mannosidase 2, alpha 1; mannosidase alpha 2; Mannosidase alpha class 2A member 1; mannosidase, alpha type II; mannosidase, alpha, class 2A, member 1; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
Gene Aliases: AMan II; GOLIM7; MAN2A1; Mana-2; MANA2; MANII; Manno; Map-2
UniProt ID: (Human) Q16706, (Mouse) P27046, (Rat) P28494
Entrez Gene ID: (Human) 4124, (Mouse) 17158, (Rat) 25478
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
zinc ion binding
hydrolase activity, hydrolyzing N-glycosyl compounds
carbohydrate binding
catalytic activity
hydrolase activity, hydrolyzing O-glycosyl compounds
alpha-mannosidase activity
mannosidase activity
hydrolase activity
hydrolase activity, acting on glycosyl bonds
metal ion binding
in utero embryonic development
liver development
carbohydrate metabolic process
mannose metabolic process
N-glycan processing
mitochondrion organization
vacuole organization
respiratory gaseous exchange
metabolic process
lung alveolus development
positive regulation of neurogenesis
retina morphogenesis in camera-type eye
protein glycosylation
protein deglycosylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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