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Proteintech
MANEA Polyclonal Antibody
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Product Details
21296-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MANEA Fusion Protein Ag15847 (29-109 aa encoded by BC146671)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LRPNTATFG APFGLDLLPE LHQRTIHLGK NFDFQKSDRI NSETNTKNLK SVEITMKPSK ASELNLDELP PLNNYLHVFY YS (29-109 aa encoded by BC146671)
Target Information
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 1,2-endomannosidase; Endo-alpha mannosidase; endomannosidase; Glycoprotein endo-alpha-1,2-mannosidase; Mandaselin; mannosidase, endo-alpha; mEndo
Gene Aliases: 4932703L02Rik; ENDO; hEndo; MANEA
UniProt ID: (Human) Q5SRI9, (Mouse) Q6NXH2
Entrez Gene ID: (Human) 79694, (Mouse) 242362
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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