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MAP1S Antibody (PA5-100607) in ICC/IF
Immunocytochemistry analysis of MAP1S in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MAP1S polyclonal antibody (Product # PA5-100607) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100607
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MAP1S(Accession Q66K74), corresponding to amino acid residues S273-D323.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2850114
Product Specific Information
Antibody detects endogenous levels of total MAP1S.
Target Information
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPY2 interacting protein 1; BPY2-interacting protein 1; MAP-1S; Microtubule-associated protein 1S; Microtubule-associated protein 8; Variable charge Y chromosome 2-interacting protein 1; VCY2 interacting protein 1; VCY2-interacting protein 1
Gene Aliases: 6430517J16Rik; BPY2IP1; C19orf5; MAP1S; MAP8; Mtap1s; VCY2IP-1; VCY2IP1
UniProt ID: (Human) Q66K74, (Rat) P0C5W1, (Mouse) Q8C052
Entrez Gene ID: (Human) 55201, (Rat) 290640, (Mouse) 270058
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