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MAP4 Antibody (PA5-96473) in IHC (P)
Immunohistochemistry analysis of MAP4 in paraffin-embedded mouse kidney. Samples were incubated with MAP4 Polyclonal antibody (Product # PA5-96473) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
PA5-96473
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 942-1152 of human MAP4 (NP_0023662)
Conjugate
Form
Liquid
Concentration
2.09 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2808275
Product Specific Information
Immunogen sequence: TENIKHQPGG GRAKVEKKTE AAATTRKPES NAVTKTAGPI ASAQKQPAGK VQIVSKKVSY SHIQSKCGSK DNIKHVPGGG NVQIQNKKVD ISKVSSKCGS KANIKHKPGG GDVKIESQKL NFKEKAQAKV GSLDNVGHLP AGGAVKTEGG GSEAPLCPGP PAGEEPAISE AAPEAGAPTS ASGLNGHPTL SGGGDQREAQ TLDSQIQETS I; Positive Samples: U-87MG; Cellular Location: Cytoplasm, cytoskeleton
Target Information
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MAP 4; MAP-4; Microtubule-associated protein 4
Gene Aliases: AA407148; MAP-4; MAP4; Mtap-4; Mtap4
UniProt ID: (Human) P27816, (Mouse) Q7TPC6
Entrez Gene ID: (Human) 4134, (Mouse) 17758
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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