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Abnova
MAPKBP1 Polyclonal Antibody, MaxPab™
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Product Details
H00023005-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MAPKBP1 (AAH36660.1, 1 a.a. approximately 1015 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGTLRVHELQ SLSEMLKVEA HDSEILCLEY SKPDTGLKLL ASASRDRLIH VLDAGREYSL QQTLDEHSSS ITAVKFAASD GQVRMISCGA DKSIYFRTAQ KSGDGVQFTR THHVVRKTTL YDMDVEPSWK YTAIGCQDRN IRIFNISSGK QKKLFKGSQG EDGTLIKVQT DPSGIYIATS CSDKNLSIFD FSSGECVATM FGHSEIVTGM KFSNDCKHLI SVSGDSCIFV WRLSSEMTIS MRQRLAELRQ RQRGGKQQGP SSPQRASGPN RHQAPSMLSP GPALSSDSDK EGEDEGTEEE LPALPVLAKS TKKALASVPS PALPRSLSHW EMSRAQESVG FLDSAPAANP GPRRRGRWVQ PGVELSVRSM LDLRQLETLA PSLQDPSQDS LAIIPSGPRK HGQEALETSL TSQNEKPPRP QASQPCSYPH IIRLLSQEEG VFAQDLEPAP IEDGIVYPEP SDNPTMDTSE FQVQAPARGT LGRVYPGSRS SEKHSPDSAC SVDYSSSCLS SPEHPTEDSE STEPLSVDGI SSDLEEPAEG DEEEEEEEGG MGPYGLQEGS PQTPDQEQFL KQHFETLASG AAPGAPVQVP ERSESRSISS RFLLQVQTRP LREPSPSSSS LALMSRPAQV PQASGEQPRG NGANPPGAPP EVEPSSGNPS PQQAASVLLP RCRLNPDSSW APKRVATASP FSGLQKAQSV HSLVPQERHE ASLQAPSPGA LLSREIEAQD GLGSLPPADG PPSRPHSYQN PTTSSMAKIS RSISVGENLG LVAEPQAHAP IRVSPLSKLA LPSRAHLVLD IPKPLPDRPT LAAFSPVTKG RAPGEAEKPG FPVGLGKAHS TTERWACLGE GTTPKPRTEC QAHPGPSSPC AQQLPVSSLF QGPENLQPPP PEKTPNPMEC TKPGAALSQD SEPAVSLEQC EQLVAELRGS VRQAVRLYHS VAGCKMPSAE QSRIAQLLRD TFSSVRQELE AVAGAVLSSP GSSPGAVGAE QTQALLEQYS ELLLRAVERR MERKL
Target Information
MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-beta-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFkappaB (nuclear factor kappa-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: JNK-binding protein 1; JNKBP-1; mitogen activated protein kinase binding protein 1; Mitogen-activated protein kinase-binding protein 1
Gene Aliases: JNKBP-1; JNKBP1; KIAA0596; MAPKBP1
UniProt ID: (Human) O60336
Entrez Gene ID: (Human) 23005
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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