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MAS1L Polyclonal Antibody

MAS1L Antibody in Immunocytochemistry (ICC/IF)

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MAS1L Antibody (20080-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using MAS1L antibody 20080-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

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Product Details

20080-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to MAS1L.

Target Information

The proto-oncogene MAS1 is a G protein-coupled receptor located on the plasma membrane. In transfected NIH/3T3 cells, MAS1 has a weak focus-inducing activity. MAS1 is an antagonist of the AT1 receptor (Angiotensin II type 1 receptor), inhibiting the actions of Angiotensin II. MAS1L (MAS1-like), also known as MAS-L or MRG (Mas-related G-protein coupled receptor MRG), is a 378 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 (GPCR) family. MAS1 related proteins are thought to regulate nociceptor function and development, including the sensation or modulation of pain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Azelaic Acid Regulates the Renin-Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation.

ACS omega

Liao Y,Wu X,Luo W,Chen J,Huang Y,Ma K,Zhang C,Wang J,Yang Y,Deng M,Wang X

Tue May 02 00:00:00 UTC 2023

Azelaic Acid Regulates the Renin-Angiotensin System and Improves Colitis Based on Network Pharmacology and Experimentation.

ACS omega

Liao Y,Wu X,Luo W,Chen J,Huang Y,Ma K,Zhang C,Wang J,Yang Y,Deng M,Wang X

Tue May 02 00:00:00 UTC 2023

Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.

Cell & bioscience

Gu G,Zhu B,Ren J,Song X,Fan B,Ding H,Shang J,Wu H,Li J,Wang H,Li J,Wei Z,Feng S

Sat Feb 04 00:00:00 UTC 2023

Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.

Cell & bioscience

Gu G,Zhu B,Ren J,Song X,Fan B,Ding H,Shang J,Wu H,Li J,Wang H,Li J,Wei Z,Feng S

Sat Feb 04 00:00:00 UTC 2023

ApoE4 associated with severe COVID-19 outcomes via downregulation of ACE2 and imbalanced RAS pathway.

Journal of translational medicine

Chen F,Chen Y,Ke Q,Wang Y,Gong Z,Chen X,Cai Y,Li S,Sun Y,Peng X,Ji Y,Zhang T,Wu W,Cui L,Wang Y

Thu Feb 09 00:00:00 UTC 2023

The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.

Microvascular research

Zhang C,Cao X,Wang H,Li Z,Zhang Y

Sat Jul 01 00:00:00 UTC 2023

Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.

Journal of ethnopharmacology

Fu S,Song X,Tang X,Qian X,Du Z,Hu Y,Xu X,Zhang M

Mon Apr 24 00:00:00 UTC 2023

The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.

Evidence-based complementary and alternative medicine : eCAM

Su JC,Cheng C,Wang CY,Zhang Y,He YT,Guo ZW,Liu XY,Liu WM,Zhang YJ,Xu SW,Zhang XY,Liu ZB,Zhang XF

Thu Oct 06 00:00:00 UTC 2022

The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.

Evidence-based complementary and alternative medicine : eCAM

Su JC,Cheng C,Wang CY,Zhang Y,He YT,Guo ZW,Liu XY,Liu WM,Zhang YJ,Xu SW,Zhang XY,Liu ZB,Zhang XF

Thu Oct 06 00:00:00 UTC 2022

The ACE2-Ang-(1‑7)-Mas Axis Modulates M1/M2 Macrophage Polarization to Relieve CLP-Induced Inflammation via TLR4-Mediated NF-кb and MAPK Pathways.

Journal of inflammation research

Pan H,Huang W,Wang Z,Ren F,Luo L,Zhou J,Tian M,Tang L

Sat Aug 10 00:00:00 UTC 2024

Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.

Neural plasticity

Feng P,Wu Z,Liu H,Shen Y,Yao X,Li X,Shen Z

Wed Apr 07 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: DAAP-341G9.4; MAS-R; mas-related G protein-coupled MRG; Mas-related G-protein coupled receptor MRG; MAS1 oncogene-like; MAS1-like; MGC119987; Mrg and gpcr

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Gene Aliases: dJ994E9.2; MAS-L; MAS1L; MRG

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UniProt ID: (Human) P35410

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Entrez Gene ID: (Human) 116511

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Function(s)

G-protein coupled receptor activity

Process(es)

G-protein coupled receptor signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MAS1L Polyclonal Antibody

MAS1L Antibody (20080-1-AP) in ICC/IF

Product Details

20080-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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