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FIGURE: 1 / 1
MATN4 Antibody (PA5-96206) in WB
Western blot analysis of MATN4 in extracts of various cell lines. Samples were incubated with MATN4 Polyclonal antibody (Product # PA5-96206) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-96206
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 221-540 of human MATN4 (NP_0850801)
Conjugate
Form
Liquid
Concentration
1.04 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808008
Product Specific Information
Immunogen sequence: FGNHSCQHEC VSTPGGPRCH CREGHDLQPD GRSCQVRDLC NGVDHGCEFQ CVSEGLSYRC LCPEGRQLQA DGKSCNRCRE GHVDLVLLVD GSKSVRPQNF ELVKRFVNQI VDFLDVSPEG TRVGLVQFSS RVRTEFPLGR YGTAAEVKQA VLAVEYMERG TMTGLALRHM VEHSFSEAQG ARPRALNVPR VGLVFTDGRS QDDISVWAAR AKEEGIVMYA VGVGKAVEAE LREIASEPAE LHVSYAPDFG TMTHLLENLR GSICPEEGIS AGTELRSPCE CESLVEFQGR TLGALESLTL NLAQLTARLE DLENQLANQK; Positive Samples: HepG2, NCI-H460, Mouse heart, Rat kidney
Target Information
Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. Members of the matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices such as embryonic kidney, lung, bone, cartilage and nervous system. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation. MATN4 could serve as an odontoblast differentiation marker, e.g. in odontoblast stem cell research.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HE6WCR54; MAT-4; Matrilin-4
Gene Aliases: MATN4; matrilin-4
UniProt ID: (Human) O95460, (Mouse) O89029
Entrez Gene ID: (Human) 8785, (Rat) 296358, (Mouse) 17183
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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