Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product is supplied at 1 mL (100 µL/mL).
Application Notes: Western Blot - A non-reduced sample treatment was used. The band sizes are 191, 263 and 316 kDa. IHC-F - Tissue sections were fixed in 4% PBS-buffered formaldehyde and pretreated with 2% hydrogen peroxide in methanol for 20 minutes at 4°C to quench endogenous peroxidases. Rat IgG2a was used as a negative control.
Regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. Necessary for centrosome duplication. It functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CpG binding domain 3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
Gene Aliases: AI181826; AU019209; Mbd3
UniProt ID: (Mouse) Q9Z2D8
Entrez Gene ID: (Mouse) 17192
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