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Proteintech
MC3R Polyclonal Antibody
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Product Details
21027-1-AP
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MC3R Fusion Protein Ag15292 (1-90 aa encoded by BC069599)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSIQKTYLE GDFVFPVSSS SFLRTLLEPQ LGSALLTAMN ASCCLPSVQP TLPNGSEHLQ APFFSNQSSS AFCEQVFIKP EVFLSLGIVS L (1-90 aa encoded by BC069599)
Target Information
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MC3 receptor; MC3-R; Melanocortin receptor 3; obesity quantitative trait locus
Gene Aliases: BMIQ9; MC3; MC3-R; MC3R; OB20; OQTL
UniProt ID: (Human) P41968, (Mouse) P33033
Entrez Gene ID: (Human) 4159, (Mouse) 17201
regulation of heart rate
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
regulation of blood pressure
positive regulation of cAMP biosynthetic process
circadian regulation of gene expression
homoiothermy
locomotor rhythm
rhythmic process
regulation of feeding behavior
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
phospholipase C-activating G-protein coupled receptor signaling pathway
sodium ion homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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