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MC5 Receptor Antibody (AMR-025-200UL) in IHC (P)
Expression of MC5R in rat skin - Immunohistochemical staining of paraffin embedded rat skin section using Anti-MC5 Receptor Antibody (#AMR-025), (1:100). MC5R staining is present in sebaceous glands. Hematoxilin is used as the counterstain.
Product Details
AMR-025-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RYNSVRQRTSMKG,corresponding to amino acid residues 224-236 of mouse MC5R, 3rd intracellular loop
Conjugate
Form
Lyophilized
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
MC5R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH), and activates adenylate cyclase. This receptor controls multiple functions in the brain and in peripheral tissues, such as thermoregulation, immunomodulation, appetite control, and sexual behavior. Melanocortin 5 receptor has been reported to be expressed in a variety of tissues, especially in pituitary, exocrine glands, reproductive organs, lung, kidney, and esophagus. No human ESTs have been isolated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H MC2; MC5; MC5 receptor; MC5-R; Melanocortin receptor 5
Gene Aliases: Mc5r
UniProt ID: (Mouse) P41149, (Rat) P35345
Entrez Gene ID: (Mouse) 17203, (Rat) 25726
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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