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          • Primary Antibodies ›
          • MC5R Antibodies

          Invitrogen

          MC5R Recombinant Rabbit Monoclonal Antibody (JE61-09)

          View all (11) MC5R antibodies
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          Datasheet
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          Cite MC5R Recombinant Rabbit Monoclonal Antibody (JE61-09)

          • Antibody Testing Data (2)
          MC5R Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          MC5R Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          MC5R Antibody (MA5-44865) in IHC (P)

          Immunohistochemistry analysis of MC-2 in paraffin-embedded mouse testis tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with MC-2 Monoclonal antibody (Product # MA5-44865) using a dilution of 1:200 for 30 minutes at room te... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MC5R Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MC5R Antibody in Western Blot (WB)

          Product Details

          MA5-44865

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          JE61-09

          Immunogen

          Synthetic peptide within human MC-2 aa 1-50/325.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          TBS, pH 7.4, with 40% glycerol, 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2931321

          Target Information

          MC5R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH), and activates adenylate cyclase. This receptor controls multiple functions in the brain and in peripheral tissues, such as thermoregulation, immunomodulation, appetite control, and sexual behavior. Melanocortin 5 receptor has been reported to be expressed in a variety of tissues, especially in pituitary, exocrine glands, reproductive organs, lung, kidney, and esophagus. No human ESTs have been isolated.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: H MC2; MC-2; MC5; MC5 receptor; MC5-R; Melanocortin receptor 5; melanocortin-5 receptor

          View more View less

          Gene Aliases: MC2; MC5R

          View more View less

          UniProt ID: (Human) P33032, (Mouse) P41149

          View more View less

          Entrez Gene ID: (Human) 4161, (Mouse) 17203

          View more View less

          Function(s)
          melanocortin receptor activity protein binding hormone binding signal transducer activity G-protein coupled receptor activity
          Process(es)
          signal transduction G-protein coupled receptor signaling pathway positive regulation of cAMP biosynthetic process G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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