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Invitrogen
MCCC2 Polyclonal Antibody
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FIGURE: 1 / 1
MCCC2 Antibody (PA5-96888) in WB
Western blot analysis of MCCC2 in extracts of various cell lines. Samples were incubated with MCCC2 Polyclonal antibody (Product # PA5-96888) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-96888
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human MCCC2 (NP_0714151)
Conjugate
Form
Liquid
Concentration
2.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808690
Product Specific Information
Immunogen sequence: LHLTRKVVRN LNYQKKLDVT IEPSEEPLFP ADELYGIVGA NLKRSFDVRE VIARIVDGSR FTEFKAFYGD TLVTGFARIF GYPVGIVGNN GVLFSESAKK GTHFVQLCCQ RNIPLLFLQN ITGFMVGREY EAEGIAKDGA KMVAAVACAQ VPKITLIIGG SYGAGNYGMC GRAYSPRFLY IWPNARISVM GGEQAANVLA TITKDQRARE GKQFSSADEA ALKEPIIKKF EEEGNPYYSS ARVWDDGIID PADTRLVLGL SFSAALNAPI EKTDFGIFRM; Positive Samples: HeLa, HepG2, K562, U-251MG, mouse liver, mouse kidney, mouse heart, rat brain, rat kidney, MCF7, 22Rv1, Mouse liver, Mouse kidney, Mouse heart, Rat brain; Cellular Location: Mitochondrion matrix
Target Information
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-methylcrotonyl-CoA carboxylase 2; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; biotin carboxylase; MCCase subunit beta; meth; methylcrotonoyl-CoA carboxylase 2 (beta); Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase; testicular secretory protein Li 29
Gene Aliases: 4930552N12Rik; MCCB; MCCC2
UniProt ID: (Human) Q9HCC0, (Rat) Q5XIT9, (Mouse) Q3ULD5
Entrez Gene ID: (Human) 64087, (Rat) 361884, (Mouse) 78038
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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