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          • Primary Antibodies ›
          • MCD Antibodies

          Invitrogen

          MCD Polyclonal Antibody

          View all (6) MCD antibodies

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          Datasheet
          Protocols
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          Cite MCD Polyclonal Antibody

          • Antibody Testing Data (3)
          MCD Antibody in Immunocytochemistry (ICC/IF)
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          MCD Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 3

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          MCD Antibody (PA5-97972) in ICC/IF

          Immunofluorescent analysis of MCD in HepG2 cells using a MCD polyclonal antibody (Product # PA5-97972) at a dilution of 1:100. Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibody was used. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MCD Antibody in Immunocytochemistry (ICC/IF)
          MCD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCD Antibody in Western Blot (WB)

          Product Details

          PA5-97972

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:5,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          Assay-Dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human Malonyl-CoA decarboxylase, mitochondrial protein (40-493AA)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          4 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2812586

          Target Information

          MCD catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: malonyl coenzyme A decarboxylase; Malonyl-CoA decarboxylase, mitochondrial; MCD

          View more View less

          Gene Aliases: MCD; MLYCD

          View more View less

          UniProt ID: (Human) O95822

          View more View less

          Entrez Gene ID: (Human) 23417

          View more View less

          Function(s)
          receptor binding malonyl-CoA decarboxylase activity
          Process(es)
          response to ischemia acetyl-CoA biosynthetic process fatty acid biosynthetic process acyl-CoA metabolic process regulation of glucose metabolic process positive regulation of fatty acid oxidation malonyl-CoA catabolic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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