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Product Details
H00023263-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MCF2L (NP_079255, 1 a.a. approximately 984 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MTVRRLSLLC RDLWALWLLL KAGADEIMHQ DIVPLCAADI QDQLKKRFAY LSGGRGQDGS PVITFPDYPA FSEIPDKEFQ NVMTYLTSIP SLQDAGIGFI LVIDRRRDKW TSVKASVLRI AASFPANLQL VLVLRPTGFF QRTLSDIAFK FNRDDFKMKV PVIMLSSVPD LHGYIDKSQL TEDLGGTLDY CHSRWLCQRT AIESFALMVK QTAQMLQSFG TELAETELPN DVQSTSSVLC AHTEKKDKAK EDLRLALKEG HSVLESLREL QAEGSEPSVN QDQLDNQATV QRLLAQLNET EAAFDEFWAK HQQKLEQCLQ LRHFEQGFRE VKAILDAASQ KIATFTDIGN SLAHVEHLLR DLASFEEKSG VAVERARALS LDGEQLIGNK HYAVDSIRPK CQELRHLCDQ FSAEIARRRG LLSKSLELHR RLETSMKWCD EGIYLLASQP VDKCQSQDGA EAALQEIEKF LETGAENKIQ ELNAIYKEYE SILNQDLMEH VRKVFQKQAS MEEVFHRRQA SLKKLAARQT RPVQPVAPRP EALAKSPCPS PGIRRGSENS SSEGGALRRG PYRRAKSEMS ESRQGRGSAG EEEESLAILR RHVMSELLDT ERAYVEELLC VLEGYAAEMD NPLMAHLLST GLHNKKDVLF GNMEEIYHFH NRIFLRELEN YTDCPELVGR CFLERMEDFQ IYEKYCQNKP RSESLWRQCS DCPFFQECQR KLDHKLSLDS YLLKPVQRIT KYQLLLKEML KYSRNCEGAE DLQEALSSIL GILKAVNDSM HLIAITGYDG NLGDLGKLLM QGSFSVWTDH KRGHTKVKEL ARFKPMQRHL FLHEKAVLFC KKREENGEGY EKAPSYSYKQ SLNMAAVGIT ENVKGDAKKF EIWYNAREEV YIVQAPTPEI KAAWVNEIRK VLTSQLQACR EASQHRALEQ SQSLPLPAPT STSPSRGNSR NIKKLEERKT DPLSLEGYVS SAPLTKPPEK GKEP
Target Information
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DBL's big sister; FLJ12122; Guanine nucleotide exchange factor DBS; MCF2 transforming sequence-like protein; MCF2-transforming sequence-like protein; RP11-98F14.2
Gene Aliases: ARHGEF14; DBS; KIAA0362; MCF2L; OST
UniProt ID: (Human) O15068
Entrez Gene ID: (Human) 23263
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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