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Invitrogen
MCHR1 Polyclonal Antibody
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Product Details
PA5-50705
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human melanin-concentrating hormone receptor 1
Conjugate
Form
Liquid
Concentration
1.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2636157
Product Specific Information
The antibody detects endogenous levels of total SLC1 / MCHR1 protein.
Target Information
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein coupled receptor 24; G protein-coupled receptor 24; G-protein coupled receptor 24; GPCR24; Gpr24-9 protein coupled receptor; MCH 1 receptor; MCH receptor 1; MCH-1R; MCH-R1; MCH1; MCH1R; MCHR; MCHR-1; Melanin-concentrating hormone receptor 1; SLC-1; Somatostatin receptor-like protein
Gene Aliases: AW049955; GPR24; MCH-1R; MCH1R; MCHR1; SLC-1; SLC1
UniProt ID: (Human) Q99705, (Mouse) Q8JZL2, (Rat) P97639
Entrez Gene ID: (Human) 2847, (Mouse) 207911, (Rat) 83567
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
positive regulation of calcium ion transport
regulation of feeding behavior
generation of precursor metabolites and energy
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
feeding behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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