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          • Primary Antibodies ›
          • MCM2 Antibodies

          Invitrogen

          MCM2 Recombinant Rabbit Monoclonal Antibody (8E8O10)

          View all (72) MCM2 antibodies

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          Datasheet
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          Datasheet
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          Cite MCM2 Recombinant Rabbit Monoclonal Antibody (8E8O10)

          • Antibody Testing Data (7)
          MCM2 Antibody in Immunocytochemistry (ICC/IF)
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          MCM2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          MCM2 Antibody (MA5-51498) in ICC/IF

          Immunocytochemistry of MCM2 in U-2 OS cells. Samples were incubated with MCM2 Recombinant monoclonal antibody (Product # MA5-51498) using a dilution of 1:300 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MCM2 Antibody in Immunocytochemistry (ICC/IF)
          MCM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCM2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCM2 Antibody in Western Blot (WB)
          MCM2 Antibody in Western Blot (WB)

          Product Details

          MA5-51498

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:20,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293 cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          8E8O10

          Immunogen

          Recombinant protein of human MCM2.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.233 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 0.05% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3093733

          Target Information

          MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: cell devision cycle-like 1; cyclin-like 1; DNA replication licensing factor MCM2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28

          View more View less

          Gene Aliases: AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; D3S3194; DFNA70; KIAA0030; MCM2; Mcmd2; MITOTIN; mKIAA0030

          View more View less

          UniProt ID: (Human) P49736, (Mouse) P97310

          View more View less

          Entrez Gene ID: (Human) 4171, (Rat) 312538, (Mouse) 17216

          View more View less

          Function(s)
          DNA binding DNA helicase activity DNA replication origin binding protein binding ATP binding enzyme binding histone binding metal ion binding nucleotide binding helicase activity hydrolase activity
          Process(es)
          G1/S transition of mitotic cell cycle DNA replication DNA unwinding involved in DNA replication DNA replication initiation nucleosome assembly cell cycle cellular response to interleukin-4
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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