Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SQLLKFVEKC SPIGVYTSGK GSSAAGLTAS VMRDPSSRNF IMEGGAMVLA DGGVVCIDEF DKMREDDRVA IHEAMEQQTI SIAKAGITTT LNSRCSVLAA ANSVFGRWDE TKGEDNIDFM PTILSRFDMI FIVKDEHNEE RDVMLAKHVI TLHVSALTQT QAVEGEIDLA KLKKFIAYCR VKCGPRLSAE AAEKLKNRYI IMRSGARQHE RDSDRRSSIP ITVRQLEAIV RIAEALSKMK LQPFATEADV EEALRLFQVS TLDAALSGTL SGVEGFTSQE DQEMLSRIEK QLKRRFAIGS QVSEHSIIKD FTKQKYPEHA IHKVLQLMLR RGEIQHRMQR KVLYRLK
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC46 homolog; DNA replication licensing factor MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; MGC5315; minichromosome maintenance deficient 5 (cell division cycle 46); P1-CDC46
Gene Aliases: CDC46; MCM5; P1-CDC46
UniProt ID: (Human) P33992
Entrez Gene ID: (Human) 4174
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support