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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MCM6 Antibodies

          Bethyl Laboratories

          MCM6 Polyclonal Antibody

          View all (26) MCM6 antibodies
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          Datasheet
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          Cite MCM6 Polyclonal Antibody

          • Antibody Testing Data (2)
          MCM6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MCM6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 2

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          MCM6 Antibody (A300-127A) in IHC (P)

          Detection of human MCM6 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified goat anti-MCM6 (Product # A300-127A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MCM6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MCM6 Antibody in Western Blot (WB)

          Product Details

          A300-127A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          -

          Immunohistochemistry (IHC)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 775 and the C-terminus (residue 821) of human Minichromosome Maintenance 6.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          phosphate/tris citrate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

          Based on 100% sequence identity, this antibody is predicted to react with Bovine

          Target Information

          MCM6 may be involved in the control of a single round of DNA replication during S phase. It binds to chromatin during G1 and detaches from it during S phase as if it licenses the chromatin to replicate.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); minichromosome maintenance deficient (mis5, S. pombe) 6; p105MCM

          View more View less

          Gene Aliases: MCG40308; MCM6; Mis5; P105MCM

          View more View less

          UniProt ID: (Human) Q14566

          View more View less

          Entrez Gene ID: (Human) 4175

          View more View less

          Function(s)
          single-stranded DNA binding ATP-dependent DNA helicase activity protein binding ATP binding identical protein binding
          Process(es)
          G1/S transition of mitotic cell cycle DNA replication DNA unwinding involved in DNA replication DNA replication initiation
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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