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Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart.
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Protein Aliases: DNA helicase MCM9; DNA replication licensing factor MCM9; hMCM9; mini-chromosome maintenance deficient 9; Mini-chromosome maintenance deficient domain-containing protein 1; Minichromosome maintenance 9; minichromosome maintenance complex component 9; minichromosome maintenance deficient domain containing 1
Gene Aliases: 9030408O17Rik; C6orf61; dJ329L24.1; dJ329L24.3; Gm235; MCM9; MCMDC1; ODG4
UniProt ID: (Human) Q9NXL9, (Mouse) Q2KHI9
Entrez Gene ID: (Human) 254394, (Mouse) 71567
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