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Invitrogen
MCT1 Recombinant Rabbit Monoclonal Antibody (9D12)
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MCT1 Antibody (MA5-38393) in IHC (P)
Immunohistochemistry (Paraffin) analysis of MCT1 in paraffin-embedded human breast cancer using MCT1 Monoclonal Antibody (Product # MA5-38393) diluted at 1:100. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is det... View More
Product Details
MA5-38393
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9D12
Immunogen
A synthesized peptide derived from human Monocarboxylic acid transporter 1 (aa 453-468).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 150mM NaCl
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898307
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ36745; MCT 1; MGC44475; monocarboxylate transporter; Monocarboxylate transporter 1; SLC16A1 protein; solute carrier family 16 (monocarboxylate transporter), member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Gene Aliases: HHF7; MCT; MCT1; MCT1D; SLC16A1
UniProt ID: (Human) P53985
Entrez Gene ID: (Human) 6566
pyruvate metabolic process
lipid metabolic process
monocarboxylic acid transport
mevalonate transport
response to food
plasma membrane lactate transport
glucose homeostasis
regulation of insulin secretion
leukocyte migration
centrosome organization
behavioral response to nutrient
cellular response to organic cyclic compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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