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Alomone Labs, LTD
MCT4 (SLC16A3) Polyclonal Antibody
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FIGURE: 1 / 2
MCT4 (SLC16A3) Antibody (AMT-014-200UL) in WB
Western blot analysis of human K562 chronic myelogenous leukemia cell line lysate (lanes 1 and 3) and human MDA-MB-231 breast adenocarcinoma cell line lysate (lanes 2 and 4): - 1,2. Anti-MCT4 (SLC16A3) Antibody (#AMT-014), (1:200).3,4. Anti-MCT4 (SLC16A3) Antibody , preincubated with MCT4/SLC16A3 Blocking Peptide (#BLP-MT014).
Product Details
AMT-014-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)REVEHFLKAEPEK, corresponding to amino acid residues 447-459 of rat MCT4, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MCT 3; MCT 4; MGC138472; MGC138474; monocarboxylate transporter; Monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; Solute carrier family 16 member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
Gene Aliases: MCT 3; MCT 4; MCT-3; MCT-4; MCT3; MCT4; SLC16A3
UniProt ID: (Human) O15427, (Mouse) P57787, (Rat) O35910
Entrez Gene ID: (Human) 9123, (Mouse) 80879, (Rat) 80878
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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