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Proteintech
MDC1 Polyclonal Antibody
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Product Details
24721-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MDC1 Fusion Protein Ag20135 (1-350 aa encoded by BC152556)
Conjugate
Form
Liquid
Concentration
0.51 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEDTQAIDW DVEEEEETEQ SSESLRCNVE PVGRLHIFSG AHGPEKDFPL HLGKNVVGRM PDCSVALPFP SISKQHAEIE ILAWDKAPIL RDCGSLNGTQ ILRPPKVLSP GVSHRLRDQE LILFADLLCQ YHRLDVSLPF VSRGPLTVEE TPRVQGETQP QRLLLAEDSE EEVDFLSERR MVKKSRTTSS SVIVPESDEE GHSPVLGGLG PPFAFNLNSD TDVEEGQQPA TEEASSAARR GATVEAKQSE AEVVTEIQLE KDQPLVKERD NDTKVKRGAG NGVVPAGVIL ERSQPPGEDS DTDVDDDSRP PGRPAEVHLE RAQPFGFIDS DTDAEEERIP ATPVVIPMKK R (1-350 aa encoded by BC152556)
Target Information
MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; Mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; Nuclear factor with BRCT domains 1
Gene Aliases: KIAA0170; MDC1; NFBD1
UniProt ID: (Human) Q14676
Entrez Gene ID: (Human) 9656
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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