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Proteintech
ME2 Polyclonal Antibody
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Product Details
24944-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ME2 Fusion Protein Ag20741 (136-480 aa encoded by BC000147)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SISDRGHVR SIVDNWPENH VKAVVVTDGE RILGLGDLGV YGMGIPVGKL CLYTACAGIR PDRCLPVCID VGTDNIALLK DPFYMGLYQK RDRTQQYDDL IDEFMKAITD RYGRNTLIQF EDFGNHNAFR FLRKYREKYC TFNDDIQGTA AVALAGLLAA QKVISKPISE HKILFLGAGE AALGIANLIV MSMVENGLSE QEAQKKIWMF DKYGLLVKGR KAKIDSYQEP FTHSAPESIP DTFEDAVNIL KPSTIIGVAG AGRLFTPDVI RAMASINERP VIFALSNPTA QAECTAEEAY TLTEGRCLFA SGSPFGPVKL TDGRVFTPGQ GNNVYIFPGY RIPIC (136-480 aa encoded by BC000147)
Target Information
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); Malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; NAD-dependent malic enzyme, mitochondrial; NAD-ME; pyruvic-malic carboxylase
Gene Aliases: ME2; ODS1
UniProt ID: (Human) P23368
Entrez Gene ID: (Human) 4200
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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