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The antibody can recognize all the isoform of MED12L. The antibody has no cross reaction to MED12.
MED12L, also named as KIAA1635, TNRC11L, TRALP and TRALPUSH, belongs to the Mediator complex subunit 12 family. MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED12L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED12L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: mediator complex subunit 12-like; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; mediator of RNA polymerase II transcription, subunit 12 homolog-like; no opposite paired repeat protein; Thyroid hormone receptor-associated-like protein; Trinucleotide repeat-containing gene 11 protein-like
Gene Aliases: A130035F20; A630079M02; AU044581; KIAA1635; Kiaa3007; MED12L; NOPAR; PRO0314; RGD1304617; TNRC11L; TRALP; TRALPUSH
UniProt ID: (Human) Q86YW9, (Mouse) Q8BQM9
Entrez Gene ID: (Human) 116931, (Mouse) 329650, (Rat) 690752
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