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Product Details
H00055588-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MED29 (NP_060062, 1 a.a. approximately 221 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLKSNGERRS RNALPAVYAR KMAASQQQAS AASSAAGVSG PSSAGGPGPQ QQPQPPAQLV GPAQSGLLQQ QQQDFDPVQR YKMLIPQLKE SLQTLMKVAA QNLIQNTNID NGQKSSDGPI QRFDKCLEEF YALCDQLELC LRLAHECLSQ SCDSAKHSPT LVPTATKPDA VQPDSLPYPQ YLAVIKAQIS CAKDIHTALL DCANKVTGKT PAPPAGPGGT L
Target Information
In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med29 (mediator complex subunit 29), also known as IXL (intersex-like), is a 200 amino acid nuclear protein and component of the mediator complex. Widely expressed in embryo and adult tissue, Med29 is considered a novel amplification target gene in pancreatic cancer and is encoded by a gene that maps to human chromosome 19q13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Intersex-like protein; Mediator complex subunit 29; Mediator of RNA polymerase II transcription subunit 29
Gene Aliases: IXL; MED2; MED29
UniProt ID: (Human) Q9NX70
Entrez Gene ID: (Human) 55588
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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