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          • Primary Antibodies ›
          • MED6 Antibodies

          Invitrogen

          MED6 Polyclonal Antibody

          View all (13) MED6 antibodies
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          Cite MED6 Polyclonal Antibody

          • Antibody Testing Data (2)
          MED6 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MED6 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          MED6 Antibody (PA5-40845) in WB

          Western blot analysis of transfected 293T cells using an anti-MED6 polyclonal antibody (Product # PA5-40845). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MED6 Antibody in Western Blot (WB)
          MED6 Antibody in ChIP Assay (CHIP)

          Product Details

          PA5-40845

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.2-1 µg/mL
          -

          ChIP assay (ChIP)

          0.5 µg
          -
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide directed towards the middle region of human MED6

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS with 2% sucrose

          Contains

          0.09% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2610035

          Product Specific Information

          Peptide sequence: ALLLDLRQKF PPKFVQLKPG EKPVPVDQTK KEAEPIPETV KPEEKETTKN

          Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 100%

          Target Information

          MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog

          View more View less

          Gene Aliases: 1500012F11Rik; AU019660; AV213303; Med6

          View more View less

          UniProt ID: (Mouse) Q921D4

          View more View less

          Entrez Gene ID: (Mouse) 69792

          View more View less

          Function(s)
          RNA polymerase II transcription cofactor activity DNA binding transcription coactivator activity protein binding transcription factor binding ubiquitin protein ligase activity
          Process(es)
          transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter protein ubiquitination stem cell population maintenance positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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