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Invitrogen
MEF2B Polyclonal Antibody
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Product Details
PA5-52095
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MEF2B. Recombinant protein control fragment (Product #RP-102465).
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643860
Product Specific Information
Immunogen sequence: VLLKYTEYSE PHESRTNTDI LETLKRRGIG LDGPELEPDE GPEEPGEKFR RLAGEGGDPA LPRPRLYPAA PAMPSPDVVY GALPPPGCDP SGLGEALPAQ SRPSPFRPAA PKAGPPGLVH PLFSPSHLTS KTPPPLYLPT E
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 62%.
Target Information
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LOC729991-MEF2B; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2BNB-MEF2B; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2
Gene Aliases: MEF2B; RSRFR2; XMEF2
UniProt ID: (Human) Q02080
Entrez Gene ID: (Human) 100271849
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase binding
protein dimerization activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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