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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MKK7 Antibodies

          Invitrogen

          MEK7 Monoclonal Antibody (4E5)

          View all (34) MKK7 antibodies

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          Datasheet
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          Datasheet
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          Cite MEK7 Monoclonal Antibody (4E5)

          • Antibody Testing Data (5)
          MEK7 Antibody in Immunocytochemistry (ICC/IF)
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          MEK7 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          MEK7 Antibody (MA5-15925) in ICC/IF

          Immunofluorescence analysis of HeLa cells using MAP2K7 monoclonal antibody (Product # MA5-15925) (Green). Red: actin filaments have been labeled with phalloidin. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MEK7 Antibody in Immunocytochemistry (ICC/IF)
          MEK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MEK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MEK7 Antibody in Western Blot (WB)
          MEK7 Antibody in Flow Cytometry (Flow)

          Product Details

          MA5-15925

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:200-1:1,000
          -

          Flow Cytometry (Flow)

          1:200-1:400
          -

          ELISA (ELISA)

          1:10,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          4E5

          Immunogen

          Purified recombinant fragment of human MAP2K7 expressed in E. Coli.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Storage buffer

          ascites

          Contains

          0.03% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11153789

          Product Specific Information

          MA5-15925 targets MAP2K7 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human samples.

          The MA5-15925 immunogen is purified recombinant fragment of human MAP2K7 expressed in E. Coli. .

          MA5-15925 detects MAP2K7 which has a predicted molecular weight of approximately 48kDa.

          Target Information

          The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; JN; JNK kinase 2; JNK-activating kinase 2; MAP kinase kinase 7; MAP2K4; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MEK 4; MEK 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK-1; SAPKK1; SEK1; Stress-activated protein kinase kinase 4

          View more View less

          Gene Aliases: JNKK2; MAP2K7; MAPKK7; MEK; MEK 7; MEK7; MKK7; PRKMK7; SAPKK-4; SAPKK4; SKK4

          View more View less

          UniProt ID: (Human) O14733

          View more View less

          Entrez Gene ID: (Human) 5609

          View more View less

          Function(s)
          magnesium ion binding receptor signaling protein serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding protein C-terminus binding JUN kinase kinase activity enzyme binding protein kinase binding protein phosphatase binding mitogen-activated protein kinase kinase kinase binding
          Process(es)
          apoptotic process response to osmotic stress signal transduction JNK cascade activation of JUN kinase activity response to heat response to UV peptidyl-tyrosine phosphorylation positive regulation of telomere maintenance via telomerase response to tumor necrosis factor proteolysis in other organism Fc-epsilon receptor signaling pathway positive regulation of neuron apoptotic process stress-activated MAPK cascade positive regulation of telomerase activity cellular response to sorbitol positive regulation of telomere capping
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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