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Product Details
PA5-62342
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MEKK6. Recombinant protein control fragment (Product #RP-101334).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643869
Product Specific Information
Immunogen sequence: EEPASPEESS GLSLLHQESK RRAMLAAVLE QELPALAENL HQEQKQEQGA RLGRNHVEEL LRCLGAHIHT PNRR
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 84%.
Target Information
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis signal-regulating kinase 2; MGC125653; MGC20114; Mitogen-activated protein kinase kinase kinase 6; OTTHUMP00000005063
Gene Aliases: ASK2; MAP3K6; MAPKKK6; MEKK6
UniProt ID: (Human) O95382
Entrez Gene ID: (Human) 9064
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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