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Invitrogen
MEOX2 Polyclonal Antibody
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MEOX2 Antibody (PA5-119768) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded rat kidney tissue using MEOX2 Polyclonal Antibody (Product # PA5-119768). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the MEOX2 antibody at a dilution of 1... View More
Product Details
PA5-119768
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human MEOX2 aa 255-304
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2913340
Product Specific Information
Positive Control: Rat kidney tissue lysates, rat kidney tissue.
Subcellular Location: Nucleus.
Target Information
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth arrest-specific homeobox; Homeobox protein MOX-2; mesenchyme homeo box 2 (growth arrest-specific homeo box); Mesenchyme homeobox 2
Gene Aliases: GAX; MEOX2; Mox-2; MOX2
UniProt ID: (Human) P50222, (Rat) P39020
Entrez Gene ID: (Human) 4223, (Rat) 29279
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
angiogenesis
somite specification
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
skeletal muscle tissue development
positive regulation of transcription from RNA polymerase II promoter
palate development
limb development
neuron death
transcription from RNA polymerase II promoter
blood circulation
negative regulation of cell migration involved in sprouting angiogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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