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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MEPE Antibodies

          Bioss

          MEPE Polyclonal Antibody

          View all (7) MEPE antibodies

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          Cite MEPE Polyclonal Antibody

          • Antibody Testing Data (1)
          MEPE Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MEPE Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MEPE Antibody (BS-8689R) in WB

          Mouse uterus lysates probed with MEPE Polyclonal Antibody, Unconjugated (bs-8689R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MEPE Antibody in Western Blot (WB)

          Product Details

          BS-8689R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human MEPE, amino acids 201-300.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Matrix extracellular phosphoglycoprotein; matrix, extracellular phosphoglycoprotein with ASARM motif (bone); OF45; Osteoblast/osteocyte factor 45; Osteoregulin

          View more View less

          Gene Aliases: MEPE; OF45

          View more View less

          UniProt ID: (Human) Q9NQ76, (Mouse) Q8K4L6

          View more View less

          Entrez Gene ID: (Human) 56955, (Mouse) 94111

          View more View less

          Function(s)
          extracellular matrix structural constituent protein binding extracellular matrix protein binding molecular_function
          Process(es)
          skeletal system development negative regulation of bone mineralization biomineral tissue development regulation of bone remodeling
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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