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Invitrogen
MEPE Polyclonal Antibody
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MEPE Antibody (PA5-121235) in WB
Western blot analysis of MEPE in extracts of various cell lines. Samples were incubated with MEPE Polyclonal antibody (Product # PA5-121235) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-121235
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 90-256 of human MEPE (NP_064588.1).
Conjugate
Form
Liquid
Concentration
0.91 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914807
Product Specific Information
Positive test controls include: HepG2, Mouse liver, Mouse spinal cord, Rat brain, Rat liver. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space.
Immunogen sequence: FTNRQRLNKE YSISNKENTH NGLRMSIYPK STGNKGFEDG DDAISKLHDQ EEYGAALIRN NMQHIMGPVT AIKLLGEENK ENTPRNVLNI IPASMNYAKA HSKDKKKPQR DSQAQKSPVK SKSTHRIQHN IDYLKHLSKV KKIPSDFEGS GYTDLQERGD NDISPFS
Target Information
Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein with ASARM motif (bone); matrix, extracellular phosphoglycoprotein with ASARM motif (bone); OF45; Osteoblast/osteocyte factor 45; Osteoregulin
Gene Aliases: MEPE; OF45
UniProt ID: (Human) Q9NQ76, (Rat) Q9ES02, (Mouse) Q8K4L6
Entrez Gene ID: (Human) 56955, (Rat) 79110, (Mouse) 94111
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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