Invitrogen

MESP1 Polyclonal Antibody

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View all (6) MESP1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-49441

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
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Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 138-173 amino acids from the Central region of Mouse Mesp1.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2634895

Target Information

Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Mesoderm posterior protein 1; MGC10676

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Gene Aliases: bHLHc5; Mesp1

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UniProt ID: (Mouse) P97309

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Entrez Gene ID: (Mouse) 17292

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding enhancer binding transcription regulatory region DNA binding protein dimerization activity
Process(es)
heart looping heart morphogenesis secondary heart field specification embryonic heart tube morphogenesis cardiac atrium formation cardiac ventricle formation sinus venosus morphogenesis growth involved in heart morphogenesis cardioblast migration transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter Notch signaling pathway multicellular organism development mesodermal cell migration neurogenesis signal transduction involved in regulation of gene expression positive regulation of Notch signaling pathway involved in heart induction negative regulation of mesodermal cell fate specification negative regulation of endodermal cell fate specification endothelial cell differentiation positive regulation of Notch signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of striated muscle cell differentiation cardiac muscle cell differentiation cardiac cell fate determination sinoatrial node cell differentiation cardiac vascular smooth muscle cell differentiation cardioblast migration to the midline involved in heart field formation positive regulation of hepatocyte differentiation positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
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