Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: GIIILKDNVA REGCILDLSD SSVTRDMDIL RSLIRKSGLV VLGQEKQDGF PEQCIPVWMF AL
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. May activate NTMT1 by priming its substrates for trimethylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha N-terminal protein methyltransferase 1B; Methyltransferase-like protein 11B; N-terminal Xaa-Pro-Lys N-methyltransferase 2; NTM1B; X-Pro-Lys N-terminal protein methyltransferase 1B
Gene Aliases: C1orf184; HOMT1B; METTL11B; NRMT2; NTM1B; NTMT2
UniProt ID: (Human) Q5VVY1
Entrez Gene ID: (Human) 149281
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