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Invitrogen
METTL7B Polyclonal Antibody
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Product Details
PA5-58478
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human METTL7B. Recombinant protein control fragment (Product #RP-97815).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643908
Product Specific Information
Immunogen sequence: RVLRPGGVLF FWEHVAEPYG SWAFMWQQVF EPTWKHIGDG CCLTRETWKD LENAQFSEIQ MERQPPPLKW LPVGPHIMGK AV
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.
Target Information
MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: associated with lipid droplets 1; Methyltransferase-like protein 7B; Thiol S-methyltransferase METTL7B; Thiol S-methyltransferase TMT1B
Gene Aliases: ALDI; METTL7B; TMT1B; UNQ594/PRO1180
UniProt ID: (Human) Q6UX53
Entrez Gene ID: (Human) 196410
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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