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MFAP5 Polyclonal Antibody

MFAP5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MFAP5 Antibody (15727-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human colon tissue slide using (Product # 15727-1-AP) (MFAP5 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Product Details

15727-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MFAP5 Fusion Protein Ag8467 (27-173 aa encoded by BC005901)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NSQRGDDVT QATPETFTED PNLVNDPATD ETVLAVLADI APSTDDLASL SEKNTTAECW DEKFTCTRLY SVHRPVKQCI HQLCFTSLRR MYIVNKEICS RLVCKEHEAM KDELCRQMAG LPPRRLRRSN YFRLPPCENV DLQRPNGL (27-173 aa encoded by BC005901 )

Target Information

This gene encodes a 25-kDa microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31- kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of ^AGTR1+ CAFs in intrahepatic cholangiocarcinoma.

Clinical and translational medicine

Li JH,Wu X,Ni X,Li YX,Xu L,Hao XY,Zhao W,Zhu XX,Yin XY

Wed Mar 01 00:00:00 UTC 2023

Development of a CAFs-related gene signature to predict survival and drug response in bladder cancer.

Human cell

Zhang Z,Liang Z,Li D,Wang L,Chen Y,Liang Y,Jiao W,Niu H

Tue Mar 01 00:00:00 UTC 2022

DPP6 and MFAP5 are associated with immune infiltration as diagnostic biomarkers in distinguishing uterine leiomyosarcoma from leiomyoma.

Frontiers in oncology

Ke Y,You L,Xu Y,Wu D,Lin Q,Wu Z

Mon Sep 09 00:00:00 UTC 2024

Microfibril Associated Protein 5 (MFAP5) Is Related to Survival of Ovarian Cancer Patients but Not Useful as a Prognostic Biomarker.

International journal of molecular sciences

Kujawa KA,Zembala-Nożynska E,Syrkis JP,Cortez AJ,Kupryjańczyk J,Lisowska KM

Thu Dec 15 00:00:00 UTC 2022

Single-cell transcriptomes reveal heterogeneity of high-grade serous ovarian carcinoma.

Clinical and translational medicine

Hao Q,Li J,Zhang Q,Xu F,Xie B,Lu H,Wu X,Zhou X

Sun Aug 01 00:00:00 UTC 2021

Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Chen Z,Yan X,Li K,Ling Y,Kang H

Wed Apr 01 00:00:00 UTC 2020

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Hepatology (Baltimore, Md.)

Marti P,Stein C,Blumer T,Abraham Y,Dill MT,Pikiolek M,Orsini V,Jurisic G,Megel P,Makowska Z,Agarinis C,Tornillo L,Bouwmeester T,Ruffner H,Bauer A,Parker CN,Schmelzle T,Terracciano LM,Heim MH,Tchorz JS

Sun Nov 01 00:00:00 UTC 2015

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Hepatology (Baltimore, Md.)

Sun Nov 01 00:00:00 UTC 2015

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Hepatology (Baltimore, Md.)

Sun Nov 01 00:00:00 UTC 2015

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Hepatology (Baltimore, Md.)

Sun Nov 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: MAGP-2; MFAP-5; Microfibril-associated glycoprotein 2; microfibril-associated glycoprotein-2; Microfibrillar-associated protein 5; MP25; THE1A-MFAP5

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Gene Aliases: AAT9; MAGP-2; MAGP2; MFAP-5; MFAP5; MP25

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UniProt ID: (Human) Q13361

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Entrez Gene ID: (Human) 8076

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Function(s)

extracellular matrix structural constituent

Process(es)

extracellular matrix organization extracellular fibril organization definitive hemopoiesis

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MFAP5 Polyclonal Antibody

MFAP5 Antibody (15727-1-AP) in IHC (P)

Product Details

15727-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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