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Product Details
PA5-59934
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MGA. Recombinant protein control fragment (Product #RP-102486).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2643931
Product Specific Information
Immunogen sequence: KLGDVKVEQQ KGFDNPEENS SEFPVTFKEE SKFELSGSKV MEQQSNLQPE AKEKECGDSL EKDRERWRKH LKGPLTRKCV GASQECKKEA DEQLIKETKT CQENSDVFQQ EQGISDLLGK SGITEDARVL KTECDSWSRI S
Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 62%.
Target Information
Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ12634; MAX dimerization protein 5; MAX gene-associated protein
Gene Aliases: KIAA0518; MAD5; MGA; MXD5
UniProt ID: (Human) Q8IWI9
Entrez Gene ID: (Human) 23269
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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