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MGAT1 Polyclonal Antibody

MGAT1 Antibody in Immunocytochemistry (ICC/IF)

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MGAT1 Antibody (15103-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using MGAT1 antibody 15103-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

MGAT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

15103-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MGAT1 Fusion Protein Ag7446 (105-445 aa encoded by BC003575)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VIPILVIAC DRSTVRRCLD KLLHYRPSAE LFPIIVSQDC GHEETAQAIA SYGSAVTHIR QPDLSSIAVP PDHRKFQGYY KIARHYRWAL GQVFRQFRFP AAVVVEDDLE VAPDFFEYFR ATYPLLKADP SLWCVSAWND NGKEQMVDAS RPELLYRTDF FPGLGWLLLA ELWAELEPKW PKAFWDDWMR RPEQRQGRAC IRPEISRTMT FGRKGVSHGQ FFDQHLKFIK LNQQFVHFTQ LDLSYLQREA YDRDFLARVY GAPQLQVEKV RTNDRKELGE VRVQYTGRDS FKAFAKALGV MDDLKSGVPR AGYRGIVTFQ FRGRRVHLAP PPTWEGYDPS WN (105-445 aa encoded by BC003575)

Target Information

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Bupivacaine reduces GlyT1 expression by potentiating the p-AMPKα/BDNF signalling pathway in spinal astrocytes of rats.

Scientific reports

Lu K,Zhao L,Zhang Y,Yang F,Zhang H,Wang J,Li B,Ji G,Yu J,Ma H

Wed Jan 26 00:00:00 UTC 2022

Bupivacaine reduces GlyT1 expression by potentiating the p-AMPKα/BDNF signalling pathway in spinal astrocytes of rats.

Scientific reports

Lu K,Zhao L,Zhang Y,Yang F,Zhang H,Wang J,Li B,Ji G,Yu J,Ma H

Wed Jan 26 00:00:00 UTC 2022

Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Liss KHH,Ek SE,Lutkewitte AJ,Pietka TA,He M,Skaria P,Tycksen E,Ferguson D,Blanc V,Graham MJ,Hall AM,McGill MR,McCommis KS,Finck BN

Fri Jan 01 00:00:00 UTC 2021

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study.

BMC cancer

Takayama H,Ohta M,Iwashita Y,Uchida H,Shitomi Y,Yada K,Inomata M

Fri Mar 06 00:00:00 UTC 2020

Blocking cellular N-glycosylation suppresses human cytomegalovirus entry in human fibroblasts.

Microbial pathogenesis

Zheng L,Li H,Fu L,Liu S,Yan Q,Leng SX

Wed Jan 01 00:00:00 UTC 2020

Reduced myocyte complex N-glycosylation causes dilated cardiomyopathy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Ednie AR,Deng W,Yip KP,Bennett ES

Tue Jan 01 00:00:00 UTC 2019

Reduced myocyte complex N-glycosylation causes dilated cardiomyopathy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Ednie AR,Deng W,Yip KP,Bennett ES

Tue Jan 01 00:00:00 UTC 2019

N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage, Secretion, and Stability.

Biochemistry

Stewart AN,Tan SY,Clark DJ,Zhang H,Wong GW

Tue Feb 12 00:00:00 UTC 2019

N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage, Secretion, and Stability.

Biochemistry

Stewart AN,Tan SY,Clark DJ,Zhang H,Wong GW

Tue Feb 12 00:00:00 UTC 2019

Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia.

Schizophrenia research

Kippe JM,Mueller TM,Haroutunian V,Meador-Woodruff JH

Sat Aug 01 00:00:00 UTC 2015

Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia.

Schizophrenia research

Kippe JM,Mueller TM,Haroutunian V,Meador-Woodruff JH

Sat Aug 01 00:00:00 UTC 2015

Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia.

Schizophrenia research

Kippe JM,Mueller TM,Haroutunian V,Meador-Woodruff JH

Sat Aug 01 00:00:00 UTC 2015

Alterations of high-mannose type N-glycosylation in human and mouse osteoarthritis cartilage.

Arthritis and rheumatism

Urita A,Matsuhashi T,Onodera T,Nakagawa H,Hato M,Amano M,Seito N,Minami A,Nishimura S,Iwasaki N

Tue Nov 01 00:00:00 UTC 2011

Alterations of high-mannose type N-glycosylation in human and mouse osteoarthritis cartilage.

Arthritis and rheumatism

Urita A,Matsuhashi T,Onodera T,Nakagawa H,Hato M,Amano M,Seito N,Minami A,Nishimura S,Iwasaki N

Tue Nov 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; GNT-I; mannoside acetylglucosaminyltransferase 1; MGAT1 gene for N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; OTTHUMP00000161546

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Gene Aliases: GGNT1; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; Gnt1; GnTI; MGAT; Mgat-1; MGAT1

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UniProt ID: (Human) P26572, (Rat) Q09325, (Mouse) P27808

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Entrez Gene ID: (Human) 4245, (Rat) 81519, (Mouse) 17308

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Function(s)

alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity metal ion binding transferase activity transferase activity, transferring glycosyl groups

Process(es)

in utero embryonic development UDP-N-acetylglucosamine catabolic process protein glycosylation carbohydrate metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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MGAT1 Polyclonal Antibody

MGAT1 Antibody (15103-1-AP) in ICC/IF

Product Details

15103-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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