Proteintech

MGAT5B Polyclonal Antibody

2 References
View all (5) MGAT5B antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

16993-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 1 publication 1 publication

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

1:20-1:200
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MGAT5B Fusion Protein Ag10678 (1-394 aa encoded by BC062354)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MITVNPDGK IMVRRCLVTL RPFRLFVLGI GFFTLCFLMT SLGGQFSARR LGDSPFTIRT EVMGGPESRG VLRKMSDLLE LMVKRMDALA RLENSSELHR AGGDLHFPAD RMPPGAGLME RIQAIAQNVS DIAVKVDQIL RHSLLLHSKV SEGRRDQCEA PSDPKFPDCS GKVEWMRARW TSDPCYAFFG VDGTECSFLI YLSEVEWFCP PLPWRNQTAA QRAPKPLPKV QAVFRSNLSH LLDLMGSGKE SLIFMKKRTK RLTAQWALAA QRLAQKLGAT QRDQKQILVH IGFLTEESGD VFSPRVLKGG PLGEMVQWAD ILTALYVLGH GLRVTVSLKE LQRQRRLRSS QEQARCGVMG ACEKMLLEGD VASNTLLIEK PSKKETEKCP KNLVT (1-394 aa encoded by BC062354)

Target Information

Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B; beta(1,6)-N-acetylglucosaminyltransferase V; beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX); GlcNAc-T Vb; GNT-IX; GNT-Vb; hGnTVb; mannoside acetylglucosaminyltransferase 5, isoenzyme B; Mannoside acetylglucosaminyltransferase 5B; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B; N-acetylglucosaminyl-transferase Vb; N-acetylglucosaminyltranferase VB; N-acetylglucosaminyltransferase IX; UDP-N-acetylglucosamine: alpha1,6-D-mannoside beta1,6-N-acetylglucosaminyltransferase b

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Gene Aliases: C330018B01; GnT-IX; GnT-VB; KIAA2008; MGAT5B; mGnTVB

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UniProt ID: (Human) Q3V5L5, (Mouse) Q765H6

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Entrez Gene ID: (Human) 146664, (Rat) 303693, (Mouse) 268510

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Function(s)
protein binding alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity metal ion binding alpha-1,6-mannosyltransferase activity alpha-1,2-mannosyltransferase activity mannosyltransferase activity alpha-1,3-mannosyltransferase activity alpha-1,3-galactosyltransferase activity UDP-glucose:glycoprotein glucosyltransferase activity glycolipid mannosyltransferase activity oligosaccharyl transferase activity dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity acetylglucosaminyltransferase activity acetylgalactosaminyltransferase activity galactosyltransferase activity fucosyltransferase activity O antigen polymerase activity lipopolysaccharide-1,6-galactosyltransferase activity transferase activity transferase activity, transferring glycosyl groups cellulose synthase activity 9-phenanthrol UDP-glucuronosyltransferase activity 1-phenanthrol glycosyltransferase activity 9-phenanthrol glycosyltransferase activity 1,2-dihydroxy-phenanthrene glycosyltransferase activity phenanthrol glycosyltransferase activity beta-1,4-mannosyltransferase activity alpha-1,2-galactosyltransferase activity dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity lipopolysaccharide-1,5-galactosyltransferase activity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity inositol phosphoceramide synthase activity glucosyltransferase activity alpha-(1->3)-fucosyltransferase activity alpha-(1->6)-fucosyltransferase activity indole-3-butyrate beta-glucosyltransferase activity salicylic acid glucosyltransferase (ester-forming) activity salicylic acid glucosyltransferase (glucoside-forming) activity benzoic acid glucosyltransferase activity chondroitin hydrolase activity dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity cytokinin 9-beta-glucosyltransferase activity
Process(es)
protein N-linked glycosylation
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