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Invitrogen
MGST1 Recombinant Rabbit Monoclonal Antibody (6A0S5)
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Product Details
MA5-42631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6A0S5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MGST1 (P10620).
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911772
Product Specific Information
Positive test controls include: HepG2, Mouse lung, Mouse liver, Rat liver. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome, Mitochondrion outer membrane, Multi-pass membrane protein, Peripheral membrane protein.
Immunogen sequence: MVDLTQVMDD EVFMAFASYA TIILSKMMLM STATAFYRLT RKVFANPEDC VAFGKGENAK KYLRTDDRVE RVRRAHLNDL ENIIPFLGIG LLYSLSGPDP
Target Information
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glutathione S-transferase 12; MGC14525; Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I
Gene Aliases: 1500002K10Rik; Gst; GST12; MGST; MGST-I; MGST1
UniProt ID: (Human) P10620, (Mouse) Q91VS7, (Rat) P08011
Entrez Gene ID: (Human) 4257, (Mouse) 56615, (Rat) 171341
glutathione metabolic process
response to organonitrogen compound
response to lipopolysaccharide
response to drug
oxidation-reduction process
protein homotrimerization
cellular response to lipid hydroperoxide
xenobiotic metabolic process
Leydig cell differentiation
cellular oxidant detoxification
glutathione derivative biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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