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Invitrogen
MGST2 Polyclonal Antibody
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FIGURE: 1 / 8
MGST2 Antibody (PA5-106675) in ICC/IF
Immunocytochemistry analysis of MGST2 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MGST2 polyclonal antibody (Product # PA5-106675) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-106675
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MGST2(Accession Q99735), corresponding to amino acid residues Y21-G71.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854343
Product Specific Information
Antibody detects endogenous levels of total MGST2.
Target Information
MGST2 (Microsomal glutathione S-transferase 2) is a 147 amino acid protein encoded by the human gene MGST2. MGST2 can catalyze the production of LTC4 (leukotriene C4) from LTA4 (leukotriene A4) and reduced glutathione. It can also catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione. MSGT2 is a multi-pass membrane protein found as a homodimer. MGST2 belongs to the MAPEG family and is expressed in liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. It has very low expression in lung, brain, placenta and bone marrow. Also, MGST2 is the only GST expressed in human umbilical vein endothelial cells (HUVECs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27438; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; MGC14097; Microsomal glutathione S-transferase 2; Microsomal glutathione S-transferase II; Microsomal GST-2; Microsomal GST-II
Gene Aliases: GST2; MGST-II; MGST2
UniProt ID: (Human) Q99735, (Mouse) A2RST1
Entrez Gene ID: (Human) 4258, (Rat) 295037, (Mouse) 211666
glutathione biosynthetic process
response to organonitrogen compound
leukotriene biosynthetic process
response to lipopolysaccharide
positive regulation of catalytic activity
oxidation-reduction process
xenobiotic metabolic process
cellular oxidant detoxification
glutathione derivative biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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