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Invitrogen
MHC Class I (RT1-A) Monoclonal Antibody (F16-4-4)
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Product Details
MA5-28196
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
F16-4-4
Immunogen
Partially purified rat MHC antigens
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2745167
Product Specific Information
This antibody recognizes the rat RT1A MHC class I antigen binding to a monomorphic epitope expressed by all rat strains, although strains of haplotype c more weakly. Mouse anti Rat MHC Class I RT1A antibody, clone F16-4-4 is routinely tested in flow cytometry on rat splenocytes.
Target Information
This protein is a non-polymorphic determinant of rat MHC Class I, which is also known as RT1-A. Rat MHC Class I is expressed on all nucleated cells and erythrocytes.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HA11; MHC class I RT1.Aa alpha-chain; Rat class I A; RT1 class I gene (A-1); RT1 class Ia, locus A (A1); RT1 class Ia, locus A1; RT1-A; RT1-AW2
Gene Aliases: RT1.A1(N); RT1A-1
Entrez Gene ID: (Rat) 24973, (Rat) 100188935
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
immune response
T cell tolerance induction
positive regulation of tolerance induction to nonself antigen
negative regulation of natural killer cell mediated cytotoxicity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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