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Invitrogen
MIB2 Polyclonal Antibody
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Product Details
PA5-66985
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human MIB2. Recombinant protein control fragment (Product #RP-107630).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664344
Product Specific Information
Immunogen sequence: PNIICDCCKKH GLRGMRWKCR VCLDYDLCTQ CYMHNKHELA HAFDRYETAH SRPVTLSPRQ GLPRIPLRGI FQ
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 93%.
Target Information
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase MIB2; EC 6.3.2.13; FLJ20648; FLJ41406; Mind bomb homolog 2; mindbomb homolog 2; Novel zinc finger protein; Novelzin; Putative NF-kappa-B-activating protein 002N; RING-type E3 ubiquitin transferase MIB2; Skeletrophin; Zinc finger ZZ type with ankyrin repeat domain protein 1; zinc finger, ZZ type with ankyrin repeat domain 1
Gene Aliases: MIB2; SKD; ZZANK1; ZZZ5
UniProt ID: (Human) Q96AX9
Entrez Gene ID: (Human) 142678
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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