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Invitrogen
MICALL2 Polyclonal Antibody
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MICALL2 Antibody (PA5-24826) in IHC (P)
Immunohistochemistry analysis of MICALL2 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with MICALL2 polyclonal antibody (Product # PA5-24826) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24826
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 841-870 amino acids from the C-terminal region of human MILK2
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542326
Target Information
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Junctional Rab13-binding protein; MICAL-L2; MICAL-like 2; MICAL-like protein 2; milk2; Molecule interacting with CasL-like 2
Gene Aliases: JRAB; MICAL-L2; MICALL2
UniProt ID: (Human) Q8IY33
Entrez Gene ID: (Human) 79778
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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