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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium binding atopy-related autoantigen 1; Calcium uptake protein 1, mitochondrial; Calcium-binding atopy-related autoantigen 1 homolog; DKFZp564C246; FLJ12684
Gene Aliases: C730016L05Rik; Calc; Cbara1; Micu1
UniProt ID: (Mouse) Q8VCX5, (Rat) Q6P6Q9
Entrez Gene ID: (Mouse) 216001, (Rat) 365567
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